Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 203-463-9 | CAS number: 107-11-9
Table 1. Measured Concentrations
Measured Allylamine Concentrations (mg/L)
Nominal Concentration (mg/L)
nd - None detected (less than the limit of detection = 0.04 mg/L)
% t0 - Measured concentration expressed as a percentage of the nominal concentration (calculated using unrounded values but expressed to 3 significant figures).
A - Culture medium incubated under test conditions without algal cells.
%N = Measured concentration expressed as a percentage of the nominal concentration (calculated using unrounded value)
* - Arithmetic mean
Table 2. Environmental Parameters
nd - None detected (less than the limit of detection of 0.04 mg/L)
See attached illustration for inhibition og growth data.
The effect of allylamine on the growth of the unicellular green alga Pseudokirchneriella subcapitata was assessed under non-axenic conditions. Due to the volatile nature of the test material the test was conducted in sealed vessels with no headspace. The study was conducted in accordance with EC Methods for Determination of Ecotoxicity, Annex IV to Commission Regulation (EC) No 761/2009 Part C, Method 3 “Freshwater Algae and Cyanobacteria, Growth Inhibition Test” and Procedure 201 of the “Guidelines for Testing of Chemicals” of the Organisation for Economic Co-operation and Development: Freshwater Alga and Cyanobacteria, Growth Inhibition Test” (2006). Replicate algal cultures, with an initial cell density of ca. 1 x 104/mL, were exposed to allylamine dispersed in algal nutrient medium at nominal concentrations of 1.03, 2.13, 4.70, 10.3, 22.7 and 50.0 mg/L. At each concentration, the test medium was prepared by the direct addition of the test substance to dilution medium (OECD medium). The cultures were incubated in an orbital incubator under continuous illumination at temperatures ranging from 22.2 to 23.6C for 72 hours. The intended exposure concentrations of allylamine were adequately achieved (between 82 and 107% of their nominal values) and maintained during the test (between 81 and 104% of their starting values) except at 4.70 mg/L, which was anomalously high (between 140 and 146% of its nominal value). Based on an arithmetic mean, the overall measured concentrations of allylamine were 0.943, 2.17, 6.71, 10.5, 23.1 and 47.2 mg/L, and these values have been used in the calculation of test results. Cell numbers were counted daily to monitor growth; the following values were derived from the data:
Average specific growth rate (0 -72h)
9.25 [8.01, 10.6]
22.3 [21.6, 23.0]
Yield (72 hours)
4.50 [3.32, 5.78]
11.2 [9.92, 12.5]
[ ] 95% confidence limits
72h EC50 (P. subcapitata) = 22.31 mg/L, 72h EC10 (P. subcapitata) = 9.25 mg/L; OECD 201; Allen (2013);
48h NOEC (C. pyroenoidosa) = 16 mg/L; similar to OECD 201; Canton and Adema (1978);
48h NOEC (S. pannonicus) = 17 mg/L; similar to OECD 201; Canton and Adema (1978);
96h NOEC (S. capricornutum) = 13 mg/L; similar to OECD 201; Canton and Adema (1978).
A single key study (Allen, 2013) is submitted for toxicity to aquatic algae. The study was conducted in accordance with OECD 201, and was conducted in accordance with GLP. All relevant validity criteria were met in this study.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
Welcome to the ECHA website. This site is not fully supported in Internet Explorer 7 (and earlier versions). Please upgrade your Internet Explorer to a newer version.
Close Do not show this message again