Registration Dossier
Registration Dossier
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EC number: 205-775-0 | CAS number: 150-84-5
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics in vitro / ex vivo
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: Publication which meets basic scientific principles
Data source
Reference
- Reference Type:
- publication
- Title:
- Toxicological assessment of flavouring esters
- Author:
- Grundschober, F.
- Year:
- 1 977
- Bibliographic source:
- Toxicology, 8(1977) 387-390
Materials and methods
Test guideline
- Qualifier:
- no guideline available
- Principles of method if other than guideline:
- Hydrolysis of flavouring esters including citronellyl acetate by pancreatin.
- GLP compliance:
- not specified
Test material
- Reference substance name:
- Citronellyl acetate
- EC Number:
- 205-775-0
- EC Name:
- Citronellyl acetate
- Cas Number:
- 150-84-5
- Molecular formula:
- C12H22O2
- IUPAC Name:
- 3,7-dimethyloct-6-en-1-yl acetate
- Test material form:
- not specified
- Details on test material:
- no details provided
Constituent 1
- Radiolabelling:
- no
Test animals
- Species:
- other: not applicable
- Strain:
- other: not applicable
Administration / exposure
- Route of administration:
- other: not applicable
- Duration and frequency of treatment / exposure:
- not applicable
Doses / concentrations
- Remarks:
- Doses / Concentrations:
not applicable
- No. of animals per sex per dose / concentration:
- not applicable
- Control animals:
- other: not applicable
Results and discussion
Metabolite characterisation studies
- Metabolites identified:
- yes
- Details on metabolites:
- ester and alcohol
Any other information on results incl. tables
After 2 hours of incubation with pancreatin, the hydrolysis of citronellyl acetate was complete (100 %). No further data given.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
