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EC number: 629-679-7 | CAS number: 42482-06-4
Solubility in organic solvents / fat solubility
Administrative data
Link to relevant study record(s)
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- Jan. 2012-June 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 111
- GLP compliance:
- yes
- Medium:
- acetone
- Solubility:
- 10 g/L
- Temp.:
- 20 °C
- Remarks on result:
- other: 5 mg/ml in acetone
- Medium:
- other: hexane
- Solubility:
- 25 mg/L
- Temp.:
- 20 °C
- Remarks on result:
- other: for calibration standards; maximum concentration was not investigated.
- Test substance stable:
- yes
- Conclusions:
- Octenyl succinic anhydride is soluble in acetone and hexane at 20 degrees C.
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 471
- Principles of method if other than guideline:
- Stability in organic solvents was investigated during a bacterial reverse mutation assay according to OECD guideline 471.
- GLP compliance:
- yes
- Medium:
- DMSO
- Temp.:
- 37 °C
- Remarks on result:
- other: no data on concentration in DMSO
- Test substance stable:
- yes
- Conclusions:
- Octenyl succinic anhydride (OSA) was found to be soluble in dimethyl sulphoxide (DMSO) in a bacterial mutagenicity protocol.
- Endpoint:
- solubility in organic solvents / fat solubility
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Study period:
- Jan. 2012-Sept. 2012
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Reason / purpose for cross-reference:
- reference to same study
- Qualifier:
- according to guideline
- Guideline:
- other: OECD 107
- Principles of method if other than guideline:
- Stability in organic solvents was investigated during the process of an n-octanol:water partition coefficient study on this substance.
- GLP compliance:
- yes
- Medium:
- acetone
- Solubility:
- 10 g/L
- Temp.:
- 22 °C
- Medium:
- other: hexane
- Solubility:
- > 25 mg/L
- Temp.:
- 22 °C
- Remarks on result:
- other: 25 mg/L was the highest level tested (as a calibration standard), and maximum solubility may be higher.
- Test substance stable:
- yes
- Conclusions:
- Octenyl succinic anhydride (OSA) was determined to be soluble and stable in organic solvents (n-octanol, hexane, acetone) as part of a study on n-octanol:water partition coefficient and substance analytical verification.
Referenceopen allclose all
Description of key information
Soluble in acetone, hexane and DMSO.
Key value for chemical safety assessment
- Solubility in organic solvents at 20°C:
- 10 g/L
Additional information
Octenyl succinic anhydride is soluble in acetone, hexane and dimethyl sulphoxide at room temperature.
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