2-Octen-1-ylsuccinic anhydride, mixture of cis and trans

Surface tension

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

surface tension

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

key study

Study period:

2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Justification for type of information:

A category approach will be used for the hazard assessment of several endpoints. The hypothesis for the category of C8-12 Alkenyl Succinic Anhydrides is that data can be read-across among members of the category because their properties and behaviours are similar, based on common functional groups and similar breakdown products, and based on a constant pattern in changing of the potency of properties of the various carbon chain lengths. These features are in accordance with Annex XI, Section 1.5, of Regulation EC No. 1907/2006.  Common functional groups are: a dihydro-2,5 -furandione (cyclic anhydride) ring, carbon chain of length 8 to 12 carbons, with or without branching methyl groups, and a single double bond in the carbon chain, location unspecified. There are no additional functional groups which would contribute incremental or different toxicity.
 
The breakdown products are the dioic acids of the corresponding anhydride; these also have common functional groups. A constant pattern may also be displayed in acute toxicity, dermal irritancy and biodegradation, with the lowest carbon chain length (C8) displaying the highest activity. Irritation, toxicity and degradation potential diminish with increasing carbon chain length. Read-across among the category members is substantiated by the common behaviour in physico-chemical and toxicity behaviours, as provided in the Chemical Category Report Format (CCRF) attached to the IUCLID file. It is adequate to fulfill the information requirements of Annex IX, to be the basis for classification and labelling decisions, and for risk assessment.

Reason / purpose for cross-reference:

read-across source

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Principles of method if other than guideline:

Wilhemy plate method

GLP compliance:

no

Type of method:

plate method

Surface tension:

28.6 mN/m

Temp.:

25 °C

Conc.:

90 vol%

The test time elapsed from sample preparation until the start of testing ranged from 27 to 60 minutes.

Conclusions:

The surface tension for octenyl succinic anhydride is estimated from the experimental value for a category member, n-dodecenyl succinic anhydride (nDDSA). nDDSA was tested for surface tension using a Wilhelmy plate method according to OECD 115. The value of a 90% saturated solution was 28.6 nM/m and is concluded to be surface active. Data can be read-across among members of the C8-12 Alkenyl Succinic Anhydrides Category, based on common functional groups, similar break-down products and potency patterns among carbon-chain length. This is adequate to fulfill the information requirements, to be the basis for classification and labelling decisions, and for risk assessment.

Reference 2

Endpoint:

surface tension

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2012

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 115 (Surface Tension of Aqueous Solutions)

Principles of method if other than guideline:

Wilhemy plate method

GLP compliance:

no

Type of method:

plate method

Surface tension:

28.6 mN/m

Temp.:

25 °C

Conc.:

90 vol%

The test time elapsed from sample preparation until the start of testing ranged from 27 to 60 minutes.

Conclusions:

The surface tension for octenyl succinic anhydride is estimated from the experimental value for a category member, n-dodecenyl succinic anhydride (nDDSA). nDDSA was tested for surface tension using a Wilhelmy plate method according to OECD 115. The value of a 90% saturated solution was 28.6 nM/m and is concluded to be surface active. Data can be read-across among members of the C8-12 Alkenyl Succinic Anhydrides Category, based on common functional groups, similar break-down products and potency patterns among carbon-chain length. This is adequate to fulfill the information requirements, to be the basis for classification and labelling decisions, and for risk assessment.

Description of key information

Surface tension is 28.6 nM/m

Key value for chemical safety assessment

Surface tension:

28.6

Additional information

The surface tension of octenyl succinic anhydride is estimated from a category member, n-Dodecenyl succinic anhydride. nDDSA was tested for surface tension according to OECD protocol 115 and found to be 28.6 nM/m. OSA and other category members are surface active.