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EC number: 272-574-2 | CAS number: 68890-66-4
Adsorption / desorption
Administrative data
Link to relevant study record(s)
Description of key information
ADSORPTIION DESORPTION BEHAVIOUR
[14C]-Octopriox Adsorption Desorption test according OECD 106
As Octopirox exists in an ionic form at higher pH it can sorb not via van der Waal forces but also by ionic interactions (e.g ion pair formation, cation exchange). So far no mechanistic model exists to estimate the sorption behaviour of these substances. Therefore measurements are warranted to address the sorption to solid phases reliably. Sorption was measured in three different soils, one sediment and one secondary sludge. The Freundlich isotherms for the different matrices are non-linear (1/n < 1). As the lowest tested concentration is used for the exposure assessment, Table 5.4-1 below lists the Kd and Koc at that concentration which allows to judge the sorption behaviour without a calculation excerise using the Freundlich isotherm.
Table 5.4 Sorption behaviour of [14C]-Octopirox to different solid matrices
SOIL |
|
% OC |
|
% Clay |
|
CEC |
Kd (L/kg) |
|
Koc (L/kg) |
Cranfield 164 |
|
3.7 |
|
28 |
|
22.8 |
4885 |
|
132027 |
|
|
|
|
|
|
||||
Cranfield 277 |
|
2.7 |
|
57 |
|
22.4 |
4800 |
|
177778 |
|
|
|
|
|
|
||||
Cranfield 299 |
|
2.9 |
|
26 |
|
14.9 |
4172 |
|
143862 |
|
|
|
|
|
|
||||
mean |
|
3.1 |
|
34 |
|
15.3 |
4619 |
|
149000 |
|
|
|
|
||||||
SEDIMENT |
|
|
|
|
|
|
|
|
|
SW |
|
6.2 |
|
25 |
|
21.7 |
3782 |
|
61000 |
|
|
|
|
|
|
||||
|
|
|
|
||||||
SLUDGE |
|
|
|
|
|
|
|
|
|
secondary (activated) |
|
37.5 |
|
59 |
|
96 |
1477 |
|
3939 |
|
|
|
|
|
|
||||
|
|
|
|
The Koc values from the OECD 106 study were used in the Environmental exposure assessment of Octopirox carried out with the EUSES model. As EUSES assigns certain percentages of organic carbon (OC) to the different compartments, Kd values for EUSES were calculate from the available Koc as given in the table 5.4-2
Table 5.4-2 Recalculation of Sorption constants for Octopirox to values which can be used in the EUSES Exposure assessment
|
OECD106 results at 10 µg/L Octopirox |
EUSES STANDARD VALUES %OC and Kd related to Koc |
|||
SOIL |
|
|
|
|
|
|
% OC |
Koc (L/kg) average |
% OC |
Kd (L/kg) EUSES |
EUSES Term for |
Cranfield 164 |
3.7 |
132027 |
|
|
|
Cranfield 277 |
2.7 |
177778 |
|
|
|
Cranfield 299 |
2.9 |
143862 |
|
|
|
mean |
3.1 |
149000 (based on mean values Kd & OC %) |
2 |
2980 |
SOIL |
SEDIMENT |
|
|
|
|
|
SW |
6.2 |
61000 |
5 |
3050 |
SEDIMENT |
SLUDGE |
|
|
|
|
|
secondary (activated) |
37.5 |
3939 |
37 |
1457 |
ACTIV. SLUDGE |
Octopirox considerably sorbs to solid matrices especially to soils and sediment.
Key value for chemical safety assessment
Additional information
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