Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: dermal
Adequacy of study:
other information

Data source

Reference
Reference Type:
other: Body responsible for the test
Title:
Unnamed

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
other: 92/69/EWG, B.3
GLP compliance:
yes
Limit test:
yes

Test animals

Species:
other: rat, Wistar Hsd Cpb:WU

Administration / exposure

Type of coverage:
semiocclusive
Vehicle:
other: none
Duration of exposure:
24 h

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 4 000 mg/kg bw
Mortality:
Male: 4000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 4000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Clinical signs:
other: Signs of toxicity related to dose levels: No signs were observed.
Gross pathology:
Effects on organs:
The necropsies performed at the end of the study revealed no
particular findings.
Other findings:
Signs of toxicity (local):
No clinical signs were observed.

There were no toxicological effects on body weight or body
weight development in males. The slight decrease in body
weight gain of the females in the first week is assumed to
be caused by the stress of the application procedure.

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU