Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 247-485-7 | CAS number: 26159-31-9
Genetic toxicity: in vitro
Administrative data
- Endpoint:
- in vitro gene mutation study in bacteria
- Remarks:
- Type of genotoxicity: gene mutation
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
Data source
Reference
- Title:
- No information
- Author:
- Benigni, R
- Year:
- 2 013
- Bibliographic source:
- OECD Toolbox v3.1 (CCRIS data from 2011)
Materials and methods
Test guideline
- Guideline:
- OECD Guideline 471 (Bacterial Reverse Mutation Assay)
- Version / remarks:
- Ames test
- GLP compliance:
- not specified
- Type of assay:
- bacterial reverse mutation assay
Test material
- Reference substance name:
- (±)-2-(6-methoxy-2-naphthyl)propionic acid
- EC Number:
- 247-485-7
- EC Name:
- (±)-2-(6-methoxy-2-naphthyl)propionic acid
- Cas Number:
- 26159-31-9
- Molecular formula:
- C14H14O3
- IUPAC Name:
- 2-(6-methoxynaphthalen-2-yl)propanoic acid
Constituent 1
Method
Species / strain
- Species / strain / cell type:
- S. typhimurium, other: TA 97A/98/100/102/1537/1538
- Metabolic activation:
- with and without
- Metabolic activation system:
- S9
Results and discussion
Test results
- Species / strain:
- S. typhimurium, other: TA 97A/98/100/102/1537/1538
- Metabolic activation:
- with and without
- Genotoxicity:
- negative
- Cytotoxicity / choice of top concentrations:
- not determined
Applicant's summary and conclusion
- Conclusions:
- Interpretation of results (migrated information):
negative
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
