Registration Dossier

Environmental fate & pathways

Adsorption / desorption

Currently viewing:

Administrative data

Link to relevant study record(s)

Description of key information

OECD 121, GLP, key study, validity 2:
Log Koc = 2.38 at 30°C.

Key value for chemical safety assessment

Koc at 20 °C:

Additional information

One valid key study is available to assess the adsorption/desorption behaviour of the test substance on soil and sewage sludge (Gancet, 2012). This study was performed in accordance with OECD testing guideline 121 and GLP requirements.

The test item is injected on a liquid chromatography system where a partition occurs between the stationary phase of the column and the eluent phase (methanol-water 55 -45 v/v). Chemicals are retained according to their adsorption coefficient. Therefore, a relation exists between the retention time and the adsorption coefficient of a chemical product. A correlation of log k' (capacity factor k') versus log Koc is plotted for the appropriate reference substances. During the analysis, the temperature was 30°C and the pH value was 7.5. Using the capacity factor and the partition coefficient of the reference items, the following calibration curve was obtained:

Log Koc = 3.1587 log k' + 2.8677 with R² = 0.9757.

The test substance contains 3 components (from 1 to 3) based on the chromatograms obtained. The mass spectrometry profile confirmed that the UV peak n°3 corresponds to the test item. The retention times for the peak n°3 were 3.16; 3.16 and 3.16 minutes for the three determinations, corresponding to area comprised between 63.04 to 63.06 % (UV, 210 nm). Log Koc, calculated using the precedent regression equation with the corresponding retention times, were 2.38; 2.38 and 2.38 for the three determinations. The average log Koc was 2.38.

All validity criteria were fulfilled. However, as a non specific detector was used, no guarantee about respective proportions of components is be provided, nor attempt of identification of peaks.

[LogKoc: 2.38]