Registration Dossier

Administrative data

Hazard for aquatic organisms

Freshwater

Hazard assessment conclusion:
PNEC aqua (freshwater)
PNEC value:
0.6 mg/L
Assessment factor:
1 000
Extrapolation method:
assessment factor
PNEC freshwater (intermittent releases):
6 mg/L

Marine water

Hazard assessment conclusion:
PNEC aqua (marine water)
PNEC value:
0.06 mg/L
Assessment factor:
10 000
Extrapolation method:
assessment factor

STP

Hazard assessment conclusion:
PNEC STP
PNEC value:
50 mg/L
Assessment factor:
100
Extrapolation method:
assessment factor

Sediment (freshwater)

Hazard assessment conclusion:
no exposure of sediment expected

Hazard for air

Air

Hazard assessment conclusion:
no hazard identified

Hazard for terrestrial organisms

Soil

Hazard assessment conclusion:
no exposure of soil expected

Hazard for predators

Secondary poisoning

Hazard assessment conclusion:
no potential for bioaccumulation

Additional information

Conclusion on classification

For 6-[[(4-methylphenyl)sulphonyl]amino]hexanoic acid (ASC plus): no classification according to the criteria laid out in regulation (EC) 1272/2008 (CLP). This is justified as follows.

available ecotoxictity data:

EC50 (fish (96 h)) = 4436 mg/L

EC50 (daphnia (48 h)) = 1173 mg/L

ErC50/ ErC10 algae (72 h) = 626/ 120 mg/L.

All effect concentrations are > 100 mg/L. Therefore, ASC plus does not need to be classified as hazardous to the aquatic environment according to the criteria of CLP-regulation (EC) 1272/2008 / Dangerous Substances Directive (67/548/EEC).