Registration Dossier
Registration Dossier
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EC number: 225-714-1 | CAS number: 5026-62-0
Endpoint summary
Administrative data
Description of key information
Additional information
The short-term toxicity to fish was determined in a study conducted by the Ministry of the Environment in Japan based on OECD-GLP standard and OECD guidelines. The LC50 after 96 hours in the species Oryzias latipes was determined to be 59.5 mg/L.
The toxicity to aquatic algae (Pseudokirchneriella subcapitata) was determined in a study based on an ISO guideline. The EC50 after 72 hours was determined to be 91 mg/L.
The short-term toxicity to Daphnia magna was determined in a study based on an ISO guideline. The EC50 after 48 hours was determined to be 11.2 mg/L.
Determination of effects in a long term toxicity study to aquatic invertebrates (OECD 211) leads to the following values:
EC 50 Reproduction (21 days): 5.32 mg/L
No Observed Effect Concentration on Reproduction (NOEC) : 0.20 mg/L
Lowest Observed Effect Concentration on Reproduction (LOEC) : 0. 81 mg/L
EC50 (mortality) for parental daphnia (21days): 0.89 mg/L
In a first zebrafish sexual development test according to OECD guideline 234 the lowest calulated NOEC was 0.11 mg/L (mean measured concentration) based on the parameter total survival.
Since this test was not valid a second test was carried out according to OECD guideline 234. The lowest calulated NOEC was 24 µg/L (mean measured concentration) based on the parameter total survival.
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