Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 206-056-4 | CAS number: 298-07-7
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 4 (not assignable)
- Rationale for reliability incl. deficiencies:
- other: insufficient documented
Data source
Reference
- Reference Type:
- publication
- Title:
- Range-finding toxicity data: List VI
- Author:
- Smyth HF, Carpenter CP, Weil CS, Pozzani UC, Striegel JA
- Year:
- 1 962
- Bibliographic source:
- Am Ind Hyg Ass J 23, 95-107, 1962
Materials and methods
- Principles of method if other than guideline:
- Groups of 6 male or female rats were exposed to concentrated vapour of bis(2-ethylhexyl) hydrogen phosphate for up to 8 hours.
- GLP compliance:
- no
- Test type:
- other: inhalation hazard test
Test material
- Reference substance name:
- Bis(2-ethylhexyl) hydrogen phosphate
- EC Number:
- 206-056-4
- EC Name:
- Bis(2-ethylhexyl) hydrogen phosphate
- Cas Number:
- 298-07-7
- Molecular formula:
- C16H35O4P
- IUPAC Name:
- bis(2-ethylhexyl) hydrogen phosphate
Constituent 1
Test animals
- Species:
- rat
- Strain:
- not specified
- Sex:
- not specified
Administration / exposure
- Route of administration:
- inhalation: vapour
- Type of inhalation exposure:
- whole body
- Vehicle:
- clean air
- Analytical verification of test atmosphere concentrations:
- no
- Concentrations:
- Rats were exposed to concentrated vapour of the test substance - but no analytical data were presented in the publication.
A saturated chamber atmosphere has a concentration of 1300 mg/m³ according the BUA report no 172. - No. of animals per sex per dose:
- 6 male or six female animals/exposure period
- Control animals:
- no
Results and discussion
Effect levels
- Sex:
- not specified
- Dose descriptor:
- LC0
- Effect level:
- > 1 300 mg/m³ air (nominal)
- Based on:
- test mat.
- Exp. duration:
- 8 h
Any other information on results incl. tables
After an exposure of 8 hours in a concentrated vapours atmosphere no animals died within 14 days.
Applicant's summary and conclusion
- Executive summary:
No animals died within 14 days after an exposure of 8 hours in a concentrated test atmosphere.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
