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Administrative data

Key value for chemical safety assessment

Additional information

In all in-vitro genetic toxicity assays (Ames tests, MNT, HGPRT test), bis(2-ethylhexyl) hydrogen phosphate was negative.

Justification for selection of genetic toxicity endpoint
The results of 3 Ames tests, an in vitro MNT test and the HPRT test were considered.

Short description of key information:
Bis(2-ethylhexyl) hydrogen phosphate was investigated in several Salmonella/microsome tests (Ames tests). Result: negative, no evidence of mutagenic activity of bis(2-ethylhexyl) hydrogen phosphate was seen (with and without mutagenic activation). Additional, bis(2-ethylhexyl) hydrogen phosphate was evaluated as negative in an in-vitro MNT and also in a HPRT test.

Endpoint Conclusion: No adverse effect observed (negative)

Justification for classification or non-classification

Due to the negative reaults in all available in-vitro genetic toxicity tests a classification is not justified.