Registration Dossier

Administrative data

Key value for chemical safety assessment

Genetic toxicity in vitro

Description of key information

Not mutagenic

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Genetic toxicity in vivo

Description of key information

Not mutagenic

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (negative)

Additional information

The substance is not considered to have mutagenic potential based on negative results in the Ames test, chromosomal aberration test and a mouse lymphoma assay, performed on the substance itself. Additionally, Ames tests, chromosomal aberration tests aa micronucleus test on structural analogues supported the findings on the substance. An in vivo chromosome aberration study on a structural analogue demonstrates that the substance is not mutagenic also in vivo.

Justification for classification or non-classification

All tests for genotoxicity are negative. No classification for mutagenicity is warranted under CLP Regulation EC no. 1272/2008.