Registration Dossier

Diss Factsheets

Administrative data

Description of key information

Lactate esters are practically non-toxic by the oral and inhalation route.

Key value for chemical safety assessment

Acute toxicity: via oral route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LD50
Value:
2 000 mg/kg bw
Quality of whole database:
Neither ethyl lactate nor ethylhexyllactate are acutely toxic by the oral route. Read-across to methyl lactate can be used to conclude that methyl lactate will not be acutely toxic either.

Acute toxicity: via inhalation route

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed
Dose descriptor:
LC50
Value:
5 400 mg/m³ air
Quality of whole database:
Neither ethyl lactate nor ethylhexyllactate are acutely toxic by the inhalation route. Read-across to methyl lactate can be used to conclude that methyl lactate will not be acutely toxic either.

Acute toxicity: via dermal route

Endpoint conclusion
Value:
mg/kg bw
Quality of whole database:
Lactate esters are practically non-toxic by the oral and inhalation route. No explicit information on acute dermal toxicity is required.

Additional information

Justification for classification or non-classification

Lactate esters are practically non-toxic by the oral and inhalation route.