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EC number: 287-488-0 | CAS number: 85536-07-8
Toxicity to microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
NOEC = 46.9 mg/L (from ready biodegradation test, 81.1% biodegradation in toxicity control within 14 days)
Key value for chemical safety assessment
Additional information
No standard studies evaluating the effect of Glycerides, C8-C10, mono- and di- (CAS No. 85536-07-8) on respiration inhibition of aquatic microorganisms are available. Therefore, a ready biodegradability study is used to derive a NOEC for this endpoint. If a compound degrades well in a ready biodegradability test, or does not inhibit the degradation of a positive control at a certain concentration, this concentration can be used as a NOEC value. This approach is in accordance with the Guidance on information requirements and chemical safety assessment (Chapter R.7b, ECHA 2012).
A substance can be assumed to be not inhibitory of the activity of aquatic microorganisms if, in the toxicity control of a ready biodegradation test, more than 25% biodegradation occurs within a period of 14 days (OECD Guideline 301). For Glycerides, C8-C10, mono- and di- a biodegradation screening test according to OECD 301B is available (Flach, 2012). This test includes a toxicity control containing 46.9 mg/L of test material. Within 14 days, 81.1% biodegradation took place in this toxicity control clearly indicating the lack of toxic potential of Glycerides, C8-C10, mono- and di- to activated sludge microorganisms, and therefore, the test item concentration of 46.9 mg/L can be used as a NOEC.
Based on the above information it is considered that Glycerides, C8-C10, mono- and di- is not inhibitory of aquatic microorganisms activity and further testing for this endpoint is not deemed necessary.
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