Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Manufacturer/producer data without proof.

Data source

Reference
Reference Type:
other company data
Title:
Unnamed
Year:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Methyl cyanoacetate
EC Number:
203-288-8
EC Name:
Methyl cyanoacetate
Cas Number:
105-34-0
Molecular formula:
C4H5NO2
IUPAC Name:
methyl 2-cyanoacetate
Details on test material:
no details on test material as used in the original study are available.

Test animals

Species:
rabbit
Strain:
not specified

Test system

Type of coverage:
not specified
Preparation of test site:
not specified
Vehicle:
not specified
Controls:
not specified
Duration of treatment / exposure:
4 hours
Observation period:
no data
Number of animals:
no data

Results and discussion

In vivo

Results
Irritation parameter:
other: no scoring values available
Remarks on result:
other: timepoints and scores not given
Irritant / corrosive response data:
The test item was designated as slightly irritating.

Applicant's summary and conclusion

Interpretation of results:
slightly irritating
Remarks:
Migrated information