Registration Dossier

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
supporting study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: secondary source

Data source

Referenceopen allclose all

Title:
No information
Author:
Cancer Res, vol 39, 2204 (1979) (citation RTECS)
Title:
No information
Author:
RTECS Number NR0200000 (1994)

Materials and methods

Principles of method if other than guideline:
intraperitoneal application of the test substance on mice
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
α,α,α-trifluoro-3-tolyl isocyanate
EC Number:
206-341-3
EC Name:
α,α,α-trifluoro-3-tolyl isocyanate
Cas Number:
329-01-1
Molecular formula:
C8H4F3NO
IUPAC Name:
α,α,α-trifluoro-3-tolyl isocyanate
Constituent 2
Reference substance name:
alpha,alpha,alpha-trifluoro-3-tolyl isocyanate
IUPAC Name:
alpha,alpha,alpha-trifluoro-3-tolyl isocyanate
Details on test material:
Test substance: no data

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Doses:
no data
No. of animals per sex per dose:
no data
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
871 mg/kg bw

Any other information on results incl. tables

no data

Applicant's summary and conclusion

Executive summary:

LD50 (i.p.) = 871 mg/kg bw (mouse)