Registration Dossier
Registration Dossier
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EC number: 270-414-6 | CAS number: 68439-70-3
Endpoint summary
Administrative data
Description of key information
Additional information
Cationic surfactants like Dimethyl alkylamines (DMAs) sorb strongly to negatively charged surfaces like glass or biota. In order to avoid sorption to the glass of the test vessel and on the test organism well characterized river was used as aquatic medium to allow relable test results. In the following the acute and chronic ecotoxictiy values in river water are given for all DMA category members to allow a direct comparison of the test results.
Short-term aquatic toxicity tests with natural river water for the DMA Category
| C10 DMA | C12 DMA | C12-14 DMA | C14 DMA | C12-16 DMA | C16 DMA | C12-18 DMA | C16-18 DMA | C16-18u DMA | C18 DMA | |
| Acute Fish Toxicity OECD 203 LC50 (96h) [mg/L] |
1.13 | 0.62 | 0.256 | 0.82 | ||||||
| Acute Daphnia Toxicity OECD 202 EC50 (48h) [ µg/L] |
926 | 55.8 | 66.5 | 188 | ||||||
| Algae Growth inhibition OECD 201 ErC50 (72h) [ µg/L] |
26.8 | 56 | 9.9 | 20.1 | 14.1 |
Long-term aquatic toxicity tests with natural river water for the DMA Category
| C10 DMA | C12 DMA | C12-14 DMA | C14 DMA | C12-16 DMA | C16 DMA | C12-18 DMA | C16-18 DMA | C16-18u DMA | C18 DMA | |
| Long-term toxicity to fish* | ||||||||||
| Long-term toxicity to Daphnia OECD 211 NOEC repro (21d) [ µg/L] |
36 | 100 | ||||||||
| Algae Growth inhibition OECD 201 ErC10 (72h) [ µg/L] |
4.3 | 20 | 2.6** | 5.9 |
* was not tested as fish is not the most sensitive species & for animal welfare reasons
** see discussion in IUCLID Chapter 6.0 PNEC & Conclusion on C&L and 6.1.5 Toxicity to algae
In addition results on the toxicity to microorganisms are given:
Tests on Sludge respriation inhibition for the DMA Category
| C10 DMA | C12 DMA | C12-14 DMA | C14 DMA | C12-16 DMA | C16 DMA | C12-18 DMA | C16-18 DMA | C16-18u DMA | C18 DMA | |
| Activated sludge respiration inhibition, OECD 209 EC50 (3h) [ mg/L] |
32.6 | 27.3 | 80 | 30.8 | 40 | 13 | 38 | 1000 |
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