Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 202-608-3 | CAS number: 97-78-9
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
Description of key information
LC50 (96 h): 107 mg/L for Danio rerio (OECD 203) (read-across)
Key value for chemical safety assessment
Fresh water fish
Fresh water fish
- Effect concentration:
- 107 mg/L
Additional information
No studies investigating the short-term toxicity of N-lauroylsarcosine (CAS 97-78-9) to fish are available. Therefore data from the corresponding salt, Sodium N-lauroylsarcosinate (CAS 137-16-6), are used as read across.
This read across approach is in accordance with Regulation (EC) No 1907/2006, Annex XI, 1.5. Grouping of substance and read across approach as is explained within the analogue justification in section 13. Since dissociation of the sodium salt under environmental conditions yields the same ionic species as dissociation of the acidic form of the substance, this read across can be considered as justified. The short-term toxicity of the read-across substance Sodium N-lauroylsarcosinate (CAS 137-16-6) to fish was investigated in one study with zebra fish (Danio rerio) according to OECD 203 and GLP (Krain, 2004). The test type (static, semi-static, flow-through) is not stated in the report and the study did not include analytics. Five nominal concentrations up to a nominal concentration of 500 mg/L were applied. The LC50 (96 h) was determined to be 107 mg/L.
Based on the available result from one structurally related read-across substance (in accordance to Regulation (EC) No 1907/2006 Annex XI, 1.5.) which is characterized by a comparable structure, it can be concluded that N-lauroylsarcosine (CAS 97-78-9) will show a similar toxicity to fish.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
