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EC number: 223-054-9 | CAS number: 3710-30-3
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
ErC50 (72 h) = 0.66; ErC50 (96 h) = 1.27 mg/L based on QSAR-calculations
Key value for chemical safety assessment
Additional information
An expert statement available for an algal growth inhibition test describes the impossibility of testing of 1,7 -octadiene in the aquatic environment due to technical reasons. As the test item is highly volatile a loss of several mg of the substance was observed in the experiment, even during weighing. Due to these properties, it was not possible to keep the concentrations of the test item within nominal ranges in the test beakers at test start (no concentration measurable at test start). Even the use of stabilisers and the use of closed vessel beakers showed no significant enhancement of the recoveries (2011 -0102 -DGO). According to the expert statement, the laboratory concluded that it is not possible to assess the toxicity of 1,7 -octadiene on algae. The statement further mentioned that the appearance of the test substance in water is very unlikely and the algal cells will not be exposed to nominal concentrations of the test item.
Nevertheless, to further cover the endpoint, QSAR-calculations were performed by using different QSAR-tools. The resulting calculated EC50-values based on growth rate were summarized in the following table.
EC50 [mg/L] |
Species |
QSAR-tool |
1.27 (96 h) |
Green algae |
EPIsuite 4.10 |
0.66 (72 h) |
Pseudokirchneriella subcapitata |
OECD Toolbox |
The calculated EC50-values for growth rate are within the range of 0.66 – 1.27 mg/L for algae, taking into account a test duration of 96 h or 72 h.
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