Registration Dossier

Diss Factsheets

Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

Currently viewing:

Administrative data

Link to relevant study record(s)

Reference
Endpoint:
toxicity to aquatic algae and cyanobacteria
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
other: Guideline 88/302/EEC
GLP compliance:
yes
Analytical monitoring:
no
Details on test solutions:
Experiment 1: 36, 60, 100, 170, 300, 500 mg/l (nominal)
Experiment 2: 12.5, 25, 50, 100, 200, 400, 800 mg/l
Test organisms (species):
Desmodesmus subspicatus (previous name: Scenedesmus subspicatus)
Details on test organisms:
TEST ORGANISMS
- Strain: Desmodesmus subspicatus (Scenedesmus subspicatus),
86.81 SAG
- Source/supplier: Institut für Wasser-, Boden- und
Lufthygiene, Berlin and Hüls AG, own breeding
- Laboratory culture: From a stem culture, prepared 3 days
prior to the start of the experiment.
- Method of cultivation: Cell density: 20000 cells/ml, culture
in sterile Erlenmeyer flasks on light-tables, light intensity:
8000 Lux, white, medium according to EC-guideline 88/302/EEC,
Test type:
static
Total exposure duration:
72 h
Test temperature:
24 +- 2 °C
pH:
pH at the beginning of the test: 7.4 to 7.6, at the end of the test: 6.8 to 9.2.
Key result
Duration:
72 h
Dose descriptor:
EC10
Effect conc.:
30.1 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
biomass
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
508.2 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
biomass
Duration:
72 h
Dose descriptor:
EC90
Effect conc.:
> 800 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
biomass
Key result
Duration:
72 h
Dose descriptor:
EC10
Effect conc.:
115.1 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
growth rate
Key result
Duration:
72 h
Dose descriptor:
EC50
Effect conc.:
> 800 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
growth rate
Duration:
72 h
Dose descriptor:
EC90
Effect conc.:
> 800 mg/L
Nominal / measured:
not specified
Conc. based on:
not specified
Basis for effect:
growth rate
Details on results:
The EC50 72h values determined by the study were 508.2 mg/L (biomass) and > 800 mg/L (growth rate), respectively.
The EC10 72h values determined by the study were 30.1 mg/L (biomass) and 115.1 mg/L (growth rate), respectively.
Validity criteria fulfilled:
not specified
Conclusions:
The EC50 72h values determined by the study were 508.2 mg/L (biomass) and > 800 mg/L (growth rate), respectively.
The EC10 72h values determined by the study were 30.1 mg/L (biomass) and 115.1 mg/L (growth rate), respectively.

Description of key information

The EC50 72h values determined by the study were 508.2 mg/L (biomass) and > 800 mg/L (growth rate), respectively.

The EC10 72h values determined by the study were 30.1 mg/L (biomass) and 115.1 mg/L (growth rate), respectively.

Key value for chemical safety assessment

EC50 for freshwater algae:
508.2 mg/L
EC10 or NOEC for freshwater algae:
30.1 mg/L

Additional information