Registration Dossier
Registration Dossier
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EC number: 218-491-7 | CAS number: 2163-00-0
Short-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
1,6-Dichlorohexane were determined in a acute immobilization test with Daphnia magna according to OECD guideline no 202. Based on the geometric mean measured concentrations of the test item, the EC50 for Daphnia magna was estimated to be 2.61 mg/L (95 % confidence limits: 2.05 - 3.28 mg/L). The NOEC after 48 h was 0.784 mg/L. The LOEC after 48 h was 1.53 mg/L.
Key value for chemical safety assessment
Fresh water invertebrates
Fresh water invertebrates
- Effect concentration:
- 2.61 mg/L
Additional information
In the key study, the influence of 1,6 -dichlorohexane on invertebrates (Daphnia magna) was investigated according to OECD guideline 202. Daphnids were exposed to the test item for 48 h under semi-static conditions. The following concentrations were tested 0.625, 1.25, 2.50, 5.00, 10.0 mg/L (corresponding to the geometric mean measured concentrations of: 0.421, 0.784, 1.53, 3.40, 6.04 mg/L). Based on the geometric mean measured concentrations of the test item, the EC50 for Daphnia magna was estimated to be 2.61 mg/L (95 % confidence limits: 2.05 - 3.28 mg/L). The NOEC after 48 h was 0.784 mg/L. The LOEC after 48 h was 1.53 mg/L.
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