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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
toxicity to other aquatic vertebrates
Type of information:
experimental study
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: Insufficent information on test methodology (measured/nominal test concentrations are not reported, no phys-chem data measured during the test). No relevant endpoint (LC1 and LC50) for evaluation of chronic effect levels.
Cross-reference
Reason / purpose for cross-reference:
reference to same study

Data source

Reference
Reference Type:
publication
Title:
Aquatic Toxicology of Trace Elements of Coal and Fly Ash.
Author:
Birge W.J.
Year:
1978
Bibliographic source:
Energy and Environmental Stress in Aquatic Systems. Ed. Thorpe, J.H. and Gibbons, J.W., Department of energy Symposium Series. pp 219-240

Materials and methods

Test guideline
Qualifier:
no guideline followed
Principles of method if other than guideline:
Semi-static embryo-larval bioassay with the narrow-mouthed toad (Gastrophryne carolensis)
GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
Divanadium pentaoxide
EC Number:
215-239-8
EC Name:
Divanadium pentaoxide
Cas Number:
1314-62-1
Molecular formula:
V2O5
IUPAC Name:
divanadium pentaoxide
Details on test material:
No information on test material stated.

Sampling and analysis

Analytical monitoring:
yes

Test solutions

Vehicle:
not specified

Test organisms

Test organisms (species):
Gastrophryne carolinensis
Details on test organisms:
Eggs

Study design

Test type:
semi-static
Water media type:
freshwater
Limit test:
no
Total exposure duration:
7 d

Test conditions

Hardness:
195±5.4 ppm CaCO3
Test temperature:
22.0±1.0°C
pH:
7.4±0.1
Dissolved oxygen:
Dissolved oxygen was maintained near saturation by continuous moderate aeration.
Nominal and measured concentrations:
Measured: 10 to 14 exposure levels.
Details on test conditions:
Eggs were exposed from fertilization through 4 days posthatching, giving treatment periods of 7 days.
Test water and toxicant were renewed at regular 12 hour intervals.
Test organisms were examined daily to tabulate frequencies of mortality and teratogenesis. Control adjusted LC1 and LC50 values were calculated for combined test responses by log probit analysis. Anomalous survivors were counted as lethals.
Control eggs were cultured simultaneously with experimentals and under identical conditions, except for omission of toxic coal elements.
Minimum sample size was set at 150 eggs per culture.
Exposure elements were initiated at 10 to 100 ppm and continued at two- to tenfold dilutions until survival of experimental animals equaled or approached that observed for controls.
Reference substance (positive control):
not specified

Results and discussion

Effect concentrationsopen allclose all
Duration:
7 d
Dose descriptor:
LC50
Effect conc.:
230 µg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
element
Remarks:
V
Basis for effect:
other: mortality and teratogenesis
Remarks on result:
other: 95% Cl: 130-410 µg V/L
Duration:
7 d
Dose descriptor:
other: LC1
Effect conc.:
7.4 µg/L
Nominal / measured:
meas. (not specified)
Conc. based on:
element
Remarks:
V
Basis for effect:
other: mortality and teratogenesis
Remarks on result:
other: 95% Cl: 0.6 - 23 µg V/L

Applicant's summary and conclusion