Registration Dossier
Registration Dossier
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EC number: 405-820-6 | CAS number: 30025-38-8
Endpoint summary
Administrative data
Description of key information
Acute p.o. toxicity study in the rat
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Dose descriptor:
- LD50
- Value:
- 4 659 mg/kg bw
Acute toxicity: via dermal route
Endpoint conclusion
- Dose descriptor:
- discriminating dose
- Value:
- 2 009 mg/kg bw
Additional information
Justification for classification or non-classification
After adjustment for relative density (0.9317) the combined male/female oral LD50 of 5.0 ml/kg and the female LD50 of 4.5 ml/kg (ca 4659 mg/kg and 4193 mg/kg respectively) are above the level for classification as toxic or R22 under directive 67/548 or for classification under regulation 1272/2008
In a guideline and GLP acute dermal toxicity limit study, the substance ethoxypropoxy propanol did not cause any mortality at a dose of 2009 mg/kg bw. No adverse clinical or pathological observations seen. Classification under directive 67/548 or regulation 1272/2008 is not therefore warranted.
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