Registration Dossier
Registration Dossier
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EC number: 205-553-3 | CAS number: 142-71-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Additional information
- Classification according to Directive 67/548/EEC: Harmful (Xn). R22, Harmful if swallowed.
- Classification according to CLP/GHS: Acute Tox. 4, H302: Harmful if swallowed.
Acute oral toxicity:
A GLP-compliant study was conducted in accordance with internationally accepted guideliunes (Bradshaw, 2012a). The acute oral median lethal dose (LD50) of the test item in the female Wistar strain rat was estimated in to be in the range of 300 - 2000 mg/kg bodyweight. On this basis, it is concluded that the following classification applies to copper di(acetate) on the basis of acute oral toxicity:
Acute inhalation toxicity:
According to criteria set out in Annex VIII of the REACH Regulation, an acute inhalation toxicity study should not be conducted if the substance is classified as corrosive to the skin. Accordingly, Copper di(acetate) is not classified on the basis of acute inhalation toxicity.
Acute dermal toxicity:
A GLP-compliant study was conducted in accordance with internationally accepted guidelines are available for acute dermal toxicity (Bradshaw, 2012b). The acute dermal median lethal dose (LD50) in the Wistar strain rat was found to be greater than 2000 mg/kg bodyweight. On this basis is is concluded that copper di(acetate) is not classified on the basis of dermal toxicity.
Justification for classification or non-classification
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