Registration Dossier
Registration Dossier
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EC number: 248-652-7 | CAS number: 27774-13-6
Endpoint summary
Administrative data
Description of key information
No reliable information available. No further testing required because vanadium oxide sulphate pentahydrate is classified as corrosive to skin.
Key value for chemical safety assessment
Acute toxicity: via oral route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via inhalation route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Acute toxicity: via dermal route
Endpoint conclusion
- Endpoint conclusion:
- no study available
Additional information
Justification for classification or non-classification
According to Annex VIII of Regulation 1907/2006, the studies on acute toxicity do not generally need to be conducted if the substance is classified as corrosive to the skin. Vanadium oxide sulphate pentahydrate is a strong acid (pH< 2) and meets the classification criteria of Regulation (EC) No 1272/2008 for Skin Corr. 1 and Serious eye damage (H314: Causes severe skin burns and eye damage.) Hence, any effects observed in an acute toxicity study does represent the corrosivity of the substance and not its intrinsic toxicity.
Specific target organ toxicant (STOT) – single exposure
The classification criteria according to Regulation (EC) 1272/2008 as specific target organ toxicant (STOT) – single exposure, oral, inhalation, or dermal are not met since adverse health effects, including reversible and irreversible, were not observed immediately or delayed after exposure. The corrosive properties of vanadium oxide sulfate lead to irritation after inhalation exposure - this was addressed with the self-classification as STOT-RE 1. No further classification is required.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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