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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

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Diss Factsheets

Ecotoxicological information

Short-term toxicity to fish

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Administrative data

Link to relevant study record(s)

Description of key information

Lawrence and Hirsch (1995) reports an LC50 for short term toxicity in fish of >1044 mg/L. 

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
1 044 mg/L

Additional information

A reliable (Klimisch 1) short-term toxicity study with fish have been conducted HQEE and is included in this dossier.


Lawrence and Hirsch (1995) conducted a reliable (Klimisch 1) GLP compliant study following OECD 203 methodsFathead minnows (Pimephales promelas) were exposed to HQEE at measured concentrations of control, 84.7, 169.2, 311.4, 566.0, and 1044.7mg/L for replicate A and 87.2, 167.3, 314.2, 574.8, and 1043.7 mg/L for replicate B under static conditions. The 96-h LC50 was >1044 mg/L, based on mortality.  


Adequate reliable measured data exists for short-term toxicity to fish for HQEE and has been documented within this dossier. The most reliable study result for the test substance has been identified as a study Lawrence and Hirsch (1995) which reports an LC50 for short term toxicity in fish of >1044 mg/L. Consequently this value will be taken as the short-term toxicity in fish endpoint for HQEE.