Registration Dossier
Registration Dossier
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EC number: 203-197-3 | CAS number: 104-38-1
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
Ward & Boeri (2004) reports a measured 72 hr EC50 of >970 mg/L and 72 hr NOEC of 500 mg/L, based on growth, for toxicity to aquatic algae.
Key value for chemical safety assessment
- EC50 for freshwater algae:
- 970 mg/L
- EC10 or NOEC for freshwater algae:
- 500 mg/L
Additional information
A reliable (Klimisch 1) toxicity study with algae has been conducted with HQEE and is included in this dossier.
Ward & Boeri (2004) conducted a reliable (Klimisch 1) GLP compliant study according to OECD 201 methods. Selenastrum capricornutum (new name: Pseudokirchnerella subcapitata) were exposed to measured concentrations (0, 63, 130, 250, 500, and 970 mg/L) of HQEE for 72 hours in a static system. The 72-hr EC50, based on growth, was >970 mg/L. The 72-hr NOEC, based on growth, was 500 mg/L.
Adequate reliable measured data exists for toxicity of HQEE to algae. The data point of highest concern for this endpoint has been identified in a reliable study which reports a measured 72 hr EC50 of >970 mg/L and 72 hr NOEC of 500 mg/L, based on growth, for toxicity to aquatic algae. Consequently these values will be taken as the toxicity in aquatic algae endpoint for HQEE.
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