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Environmental fate & pathways

Hydrolysis

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Description of key information

The rate of hydrolysis of the substance at pH values normally found in the environment (pH 4-9) was determined according to OECD 111 and GLP principles. The test substance shows a pseudo-first order behaviour. Half-life times at 25°C and pH 4, pH 7 and pH 9 were determined to be 17, 4.3 and 19 hours, respectively. 

Key value for chemical safety assessment

Half-life for hydrolysis:
4.3 h
at the temperature of:
25 °C

Additional information

The rate of hydrolysis of the substance at pH values normally found in the environment (pH 4-9) was determined according to OECD 111 and GLP principles. A preliminary test was not performed as the substance was known to be hydrolytically unstable in water (see water solubility), thus a Tier 2 main study was performed at pH 4, 7 and 9 at 20, 40 and 50°C. The mean recoveries fell between 90 -110% for pH 7 and 9, while for pH 4 these were above 110%. As the hydrolysis concentrations were based on the relative concentrations, these recoveries were accepted. The test substance shows a pseudo-first order behaviour. Half-life times as 25°C and pH 4, pH 7 and pH 9 were determined to be 17, 4.3 and 19 hours, respectively. The half-life time at pH 7 is given as the key value for CSA as the highest rate of hydrolysis was measured at this pH.