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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
migrated information: read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The analogue shares the same functional groups with the substance and also has comparable values for the relevant molecular properties.

Data source

Reference
Reference Type:
other: Read-across approach from data on an analogue.
Title:
Unnamed
Year:
2012

Materials and methods

Principles of method if other than guideline:
Read-across approach from data on an analogue.
GLP compliance:
yes (incl. QA statement)

Test material

Constituent 1
Reference substance name:
Automatically generated during migration to IUCLID 6, no data available
IUPAC Name:
Automatically generated during migration to IUCLID 6, no data available
Details on test material:
See attached document "Reporting format for the analogue approach".

Results and discussion

Effect levels
Sex:
female
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Based on the read-across approach from data on an analogue, the oral LD50 is considered to be greater than 2000 mg/kg bw.
Executive summary:

The analogue shares the same functional groups with the substance and also has comparable values for the relevant molecular properties.

Based on the read-across approach from data on an analogue, the oral LD50 is considered to be greater than 2000 mg/kg bw.