Registration Dossier
Registration Dossier
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EC number: 272-195-2 | CAS number: 68783-37-9 This substance is identified by SDA Substance Name: C16-C18 alkyl carboxylic acid lithium salt and SDA Reporting Number: 19-006-02.
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation: in vitro
- Type of information:
- read-across based on grouping of substances (category approach)
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Justification for type of information:
- See IUCLID section 13 for category and read across justification
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 020
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 442D (In Vitro Skin Sensitisation: ARE-Nrf2 Luciferase Test Method)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of study:
- activation of keratinocytes
Test material
- Reference substance name:
- Lithium myristate
- EC Number:
- 243-743-8
- EC Name:
- Lithium myristate
- Cas Number:
- 20336-96-3
- Molecular formula:
- C14H28O2.Li
- IUPAC Name:
- lithium myristate
- Reference substance name:
- Lithium laurate
- EC Number:
- 238-663-5
- EC Name:
- Lithium laurate
- Cas Number:
- 14622-13-0
- Molecular formula:
- C12H24O2.Li
- IUPAC Name:
- lithium laurate
- Reference substance name:
- Lithium palmitate
- EC Number:
- 243-842-6
- EC Name:
- Lithium palmitate
- Cas Number:
- 20466-33-5
- Molecular formula:
- C16H32O2.Li
- IUPAC Name:
- lithium palmitate
- Reference substance name:
- Lithium hydroxide
- EC Number:
- 215-183-4
- EC Name:
- Lithium hydroxide
- Cas Number:
- 1310-65-2
- Molecular formula:
- HLiO
- IUPAC Name:
- lithium hydroxide
- Test material form:
- solid
- Details on test material:
- - Batch number: A194-99/3
- Expiry date: 02 April 2022
Constituent 1
impurity 1
impurity 2
impurity 3
Results and discussion
In vitro / in chemico
Results
- Key result
- Remarks on result:
- other: Test currently ongoing
- Remarks:
- Test currently ongoing
Applicant's summary and conclusion
- Interpretation of results:
- other:
- Remarks:
- Test currently ongoing
- Conclusions:
- The skin sensitisation potential of lithium myristate was determined to be
- Executive summary:
The skin sensitisation potential of lithium myristate in the in vitro OECD 442D Keratinosens test was determined to be
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