rac-(1R,4S,4aR,8R,8aS)-9-(dichloromethylidene)-8-hydroxyoctahydro-1,4-methanonaphthalen-5(1H)-one

Flammability

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

flammable solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

20 Jan 2015 to 27 Feb 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.1 (Test method for readily combustible solids)

Version / remarks:

2009

Deviations:

no

GLP compliance:

yes

Key result

Test procedure:

burning rate test: preliminary screening test

Remarks on result:

substance does not ignite and propagate combustion either by burning with flame or smouldering along 200 mm of the powder train within the 2 minutes test period

Remarks:

full test is not required

Interpretation of results:

not classified based on GHS criteria

Conclusions:

The test substance did not propagate combustion.. In accordance with the criteria of UN Test N.1, the test substance is not classified as a flammable solid.

Executive summary:

The flammability of the test substance was determined in accordance with UN Test N.1: “Test Method for Readily Combustible Solids”, in order to establish the ability of the substance to propagate combustion, under GLP conditions. The test substance did not propagate combustion.. and therefore the test substance is not classified as a flammable solid.

Reference 2

Endpoint:

pyrophoric solids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

20 Jan 2015 to 27 Feb 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.2 (Test method for pyrophoric solids)

Version / remarks:

2009

Deviations:

no

GLP compliance:

yes

Key result

Test procedure:

ignition time on contact with air

Temp.:

23 °C

Remarks on result:

no ignition on contact with air (not further specified)

Interpretation of results:

not classified based on GHS criteria

Conclusions:

The test substance does not spontaneously ignite on contact with air at ambient temperatures. In accordance with the criteria of UN Test N.2, the test substance is not classified as pyrophoric solid.

Executive summary:

The pyrophoric properties of the test item were tested in accordance with UN Test N.2: “Test Method for Pyrophoric Solids”. The test substance was exposed to air at ambient temperature. The sample is observed during dropping and for a further 5 minutes after settling for any signs of ignition. The test is carried out six times. The test substance does not spontaneously ignite on contact with air at ambient temperatures. In accordance with the criteria of UN Test N.2, the test substance is not classified as pyrophoric solid.

Reference 3

Endpoint:

self-heating substances / mixtures

Type of information:

experimental study

Adequacy of study:

key study

Study period:

20 Jan 2015 to 27 Feb 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.4 (Test method for self-heating substances)

Version / remarks:

2009

Deviations:

no

GLP compliance:

yes

Key result

Remarks on result:

not determinable because of methodological limitations

Remarks:

The substance melted during the test and drained from the basket. The test cannot be applied to this material and no conclusions can be drawn.

Details on results:

The test substance has a melting point close to the test temperature. In order to establish whether or not the wire mesh baskets would be able to contain the test substance

throughout the course of the test, the smaller 25 mm basket test at 140°C was carried out first to avoid unnecessary sample wastage. 

- The temperature/time trace shows a small initial exothermic peak, with the test sample reaching a maximum temperature of 149°C, after which it returns to a temperature close to that of the oven for the rest of the test.

- On inspection after the test, the basket was observed to be empty. This behaviour is consistent with the sample having melted and drained out of the basket during the test.

Interpretation of results:

study cannot be used for classification

Conclusions:

The self-heating characteristics of the test substance could not be determined from UN Test N.4. It is not possible to make a definitive classification without being able to perform the 100 mm and 25 mm basket tests at 140 °C. The wire-mesh construction of the containers specified for use in this test is inappropriate for materials such as the test substance, which melt at or near the test temperature.

Executive summary:

The self-heating properties of the test item were tested in accordance with the UN Test N.4: “Test Method for Self-Heating Substances”. The test volumes, temperature and criteria for classification are based on the self-ignition temperature of charcoal, which is 50°C for volumes of 27 m3 and 140°C for volumes of 1 L. The test substance had a melting point close to the test temperature. In order to establish whether or not the wire mesh baskets would be able to contain the test substance throughout the course of the test, the smaller 25 mm basket test at 140°C was carried out first to avoid unnecessary sample wastage. Therefore, the self-heating characteristics of the test substance could not be determined from UN Test N.4.  It is not possible to make a definitive classification without being able to perform the 100 mm and 25 mm basket tests at 140 °C. The wire-mesh construction of the containers specified for use in this test is inappropriate for materials such as the test substance, which melt at or near the test temperature.

Reference 4

Endpoint:

substances / mixtures which in contact with water emit flammable gases

Type of information:

experimental study

Adequacy of study:

key study

Study period:

20 Jan 2015 to 27 Feb 2015

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

UN Manual of Tests and Criteria: Test N.5 (Test method for substances which in contact with water emit flammable gases)

Version / remarks:

2009

Deviations:

no

GLP compliance:

yes

Key result

Test procedure:

step 4

Identity of evolved gas:

not applicable as no gas evolved

Remarks on result:

no reaction with water observed

Remarks:

No gas was evolved on contact with water over a period of 7 hours in each of the three tests.

Test procedure:

step 3

Remarks on result:

no reaction with water observed

Test procedure:

step 2

Remarks on result:

no reaction with water observed

Test procedure:

step 1

Remarks on result:

no reaction with water observed

Step 4 results:

Sample preparation:  Tested as received.

Room temperature:   22 - 23°C.

Water temperature:   23°C.

Interpretation of results:

not classified based on GHS criteria

Conclusions:

The test substance does not evolve flammable gases on contact with water. In accordance with the criteria of UN Test N.5, the test substance is not classified as a substance which, in contact with water, emits flammable gases.

Executive summary:

Water reactivity was tested in accordance with the UN Test N.5: “Test Method for Substances Which in Contact with Water Emit Flammable Gases”. Three preliminary screening tests, using small quantities of the test substance, are carried out to determine whether or not any gas is evolved on contact with water and if so, whether or not it spontaneously ignites. The spontaneous ignition of any evolved gases in one of the screening tests is sufficient for the positive classification of the test substance, and no further testing is necessary.In the absence of a positive result in any of the screening tests, the following test, Step 4, is carried out in triplicate. No gas was evolved on contact with water over a period of 7 hours in each of the three tests. The test substance does not evolve flammable gases on contact with water. In accordance with the criteria of UN Test N.5, the test substance is not classified as a substance which, in contact with water, emits flammable gases.

Description of key information

Flammability: The test substance did not propagate combustion. The test substance is not classified as a flammable solid, UN test N.1, Jackson 2015

Pyrophoric properties: The test substance does not spontaneously ignite on contact with air at ambient temperatures, UN test N.2, Jackson 2015

Self-heating properties: It is not possible to make a definitive classification without being able to perform the 100 mm and 25 mm basket tests at 140 °CU, N test N.4, Jackson 2015

Water reactivity: The test substance does not evolve flammable gases on contact with water, UN test N.5, jackson 2015

Key value for chemical safety assessment

Flammability:

not classified

Additional information

 The flammability of the test substance was determinedin accordance with UN Test N.1: “Test Method for Readily Combustible Solids”, in order to establish the ability of the substance to propagate combustion, under GLP conditions.The test substance did not propagate combustion.. and therefore the test substance is not classified as a flammable solid. The pyrophoric properties of the test item were tested in accordance with UN Test N.2: “Test Method for Pyrophoric Solids”. The test substance was exposed to air at ambient temperature. The sample is observed during dropping and for a further 5 minutes after settling for any signs of ignition. The test is carried out six times.The test substance does not spontaneously ignite on contact with air at ambient temperatures. In accordance with the criteria of UN Test N.2, the test substance is not classified as pyrophoric solid. The self-heating characteristics of the test substance could not be determined from UN Test N.4. It is not possible to make a definitive classification without being able to perform the 100 mm and 25 mm basket tests at 140 °C. The wire-mesh construction of the containers specified for use in this test is inappropriate for materials such as the test substance, which melt at or near the test temperature. Water reactivity was tested in accordance with the UN Test N.5: “Test Method for Substances Which in Contact with Water Emit Flammable Gases”. Three preliminary screening tests, using small quantities of the test substance, are carried out to determine whether or not any gas is evolved on contact with water and if so, whether or not it spontaneously ignites. The spontaneous ignition of any evolved gases in one of the screening tests is sufficient for the positive classification of the test substance, and no further testing is necessary.In the absence of a positive result in any of the screening tests, the following test, Step 4, is carried out in triplicate. No gas was evolved on contact with water over a period of 7 hours in each of the three tests. The test substance does not evolve flammable gases on contact with water. In accordance with the criteria of UN Test N.5, the test substance is not classified as a substance which, in contact with water, emits flammable gases (Jackson, 2015). All studies are considered to be relevant, reliable (Klimisch 1) and adequate for the purposes of risk assessment, classification and labelling.

Justification for classification or non-classification

The available experimental test data are considered reliable and suitable for classification purposes under Regulation (EC) No. 1272/2008.[SdG1] 

The substance is not considered to be a flammable solid, pyrophoric solid, self-heating substance or reactive with water to emit flammable gases according to the criteria given in test methods N1, N2, N4 and N5 of the UN Recommendations on the Transport of Dangerous Goods, Manual of Tests and Criteria, Part III. As a result the substance is not considered to be classified for flammability under EU Classification, Labelling and Packaging of Substances and Mixtures (CLP) Regulation (EC) No. 1272/2008.