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Toxicological information

Dermal absorption

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Administrative data

Endpoint:
dermal absorption
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Data taken from short database entry, not according to standard protocols

Data source

Reference
Reference Type:
secondary source
Title:
Penetrating agents.
Author:
F.Meyer
Year:
1965
Bibliographic source:
Patent, British, 1,001,949, M49750IVa/30h, 7/20/61; cited in RIFM/FEMA database, location 21664

Materials and methods

Principles of method if other than guideline:
No guideline followed

Test material

Constituent 1
Chemical structure
Reference substance name:
Geranyl acetate
EC Number:
203-341-5
EC Name:
Geranyl acetate
Cas Number:
105-87-3
Molecular formula:
C12H20O2
IUPAC Name:
3,7-dimethylocta-2,6-dien-1-yl acetate

Test animals

Species:
guinea pig

Administration / exposure

Vehicle:
other: usually 50% ethyl glycol
Duration of exposure:
2 hours
Doses:
50%
No furhter data given

Results and discussion

Any other information on results incl. tables

epithelium (epi): = (slight coloring/fluorescence)

hair follicles (hf): = (slight coloring/fluorescence)

corium (c): - (no coloring/fluorescence).

subcutis (sc): - (no coloring/fluorescence).

Applicant's summary and conclusion