Registration Dossier
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EC number: 288-305-7 | CAS number: 85711-45-1
Long-term toxicity to aquatic invertebrates
Administrative data
Link to relevant study record(s)
Description of key information
No chronic effects to aquatic invertebrates up to the limit of water solubility (< 0.05 mg/L).
Key value for chemical safety assessment
Additional information
One study investigating the long-term toxicity of fatty acids, C16-18 and C18-unsaturated, esters with pentaerythritol (CAS 85711-45-1) to aquatic invertebrates is available (Schlechtriem, 2013). The GLP study was conducted under semi-static conditions according to OECD 211 using Daphnia magna as test organism. A loading rate of 1 mg/L (nominal) was applied in the limit test. No significant effect on reproduction, mean age of first brood and immobilisation was observed in the treatment throughout the test period of 21 d. A difference between the mean length of the control and treatment group was < 10% (i.e. 6.04%) and is therefore be considered as biologically not relevant. Hence, the 21 d-NOELR is determined to be ≥ 1 mg/L on the basis of the nominal test concentration, i.e. no effects occurred up to the limit of water solubility (< 0.05 mg/L). As it can be seen in the data matrix of the category justification in section 13 and the overall endpoint summary IUCLID 6.1, all reliable data in the category support the hazard assessment of each category member by showing a consistent pattern of results, i.e. no toxic effects to aquatic organisms were observed up to the limit of water solubility.
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