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Ecotoxicological information

Short-term toxicity to fish

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Description of key information

An acute toxicity study (96 h) was conducted by Gonsior, G. (2009) according to OECD 203 (1992) guideline, with Oncorhynchus mykiss (10 fish per concentration). It was performed under semi-static conditions, with following concentrations: 0, 0.625, 1.25, 2.5, 5 and 10 mg/L. The LC0 (96 h) was 5 mg/L (nominal) and the NOEC (96 h) was at 0.625 mg/L. No lethal or sublethal effects were observed in the control. In the solvent control one fish died. At 1.25, 2.5 and 5 mg/L the fish were affected by the test item. At 10 mg/L 100% of the fish died within 48 h. The LC50 (96 hours) was 7.07 mg/L.

Key value for chemical safety assessment

Fresh water fish

Fresh water fish
Effect concentration:
7.07 mg/L

Additional information

The study of Gonsior, G. (2009) was conducted according to OECD 203 (1992) guideline and was found to be valid with LC50 of 7.07 mg of Piperonyl butoxide/L after 96 hours. The study is considered as "reliable without restriction".

The results are summarised in the following table:

Species Endpoint (exposure duration) Exposure concentration  Reference
 Oncorhynchus mykiss  LC50(48, 72, 96 h)   7.07 mg/L  Gonsior, G. (2009)