Registration Dossier

Diss Factsheets

Administrative data

Endpoint:
phototransformation in water
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: GLP study according to EU/OECD guideline.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2002

Materials and methods

Study type:
direct photolysis
Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline draft (Phototransformation of Chemicals in Water - Direct and Indirect Photolysis)
GLP compliance:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
2-chlorobenzamide
EC Number:
210-195-6
EC Name:
2-chlorobenzamide
Cas Number:
609-66-5
Molecular formula:
C7H6ClNO
IUPAC Name:
2-chlorobenzamide

Study design

Radiolabelling:
yes
Analytical method:
high-performance liquid chromatography
Light source:
other: mercury immersion lamp TQ 150 (Original Hanau Co.).
Light spectrum: wavelength in nm:
>= 295 - <= 490
Relative light intensity:
>= 1.3 - <= 100
Duration of test at given test condition
Duration:
500 min
Temp.:
25 °C
Initial conc. measured:
5.28 mg/L
Reference substance:
no
Dark controls:
no

Results and discussion

Quantum yield (for direct photolysis):
0.002
Predicted environmental photolytic half-life:
The estimates based on two different arithmetic models (GC-SOLAR and Frank & Klöpffer) by means of the resulting quantum yield and the light
absorption in a range of wavelengths relevant for the environment were well comparable when considering identical marginal conditions. "Environmental direct photolysis half-lives" of more than 95 days can be calculated for the test item.

Applicant's summary and conclusion

Validity criteria fulfilled:
yes
Conclusions:
Only very weak degradation of the test item was measured by HPLC-UV during the maximum irradiation period of 500 minutes in pure water. This indicated a high stability of the test item against direct photo-degradation in aqueous solution relative to other compounds irradiated under the
same study conditions.
However, this assessment does not consider any indirect mechanisms, which may enhance the photodegradation in natural water.

Categories Display