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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
water solubility
Type of information:
experimental study
Adequacy of study:
key study
Study period:
July 29, 2013 - November 7, 2013
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study was performed in accordance with the EC A.6 and OECD 105 guidelines and complied with the principles of GLP.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2013
Report date:
2013

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.6 (Water Solubility)
Version / remarks:
(2008)
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 105 (Water Solubility)
Version / remarks:
(1995)
Deviations:
no
Qualifier:
according to guideline
Guideline:
EPA OPPTS 830.7840 (Water Solubility)
Version / remarks:
(1998)
Deviations:
no
GLP compliance:
yes
Type of method:
column elution method

Test material

Constituent 1
Chemical structure
Reference substance name:
2-[3-(9-butyl-1,1,3,3,5,5,7,7,9,9-decamethylpentasiloxanyl)propoxy]ethyl methacrylate
EC Number:
801-072-3
Cas Number:
1052075-57-6
Molecular formula:
C23H54O7Si5
IUPAC Name:
2-[3-(9-butyl-1,1,3,3,5,5,7,7,9,9-decamethylpentasiloxanyl)propoxy]ethyl methacrylate
Details on test material:
- Name of test material (as cited in study report): KF-1622
- Description: Clear colourless liquid
- Storage condition of test material: In refrigerator (2-8°C) in the dark
- Expiration date of the lot/batch: May 17, 2014

Results and discussion

Water solubilityopen allclose all
Water solubility:
0.015 mg/L
Temp.:
20 °C
pH:
6.9
Remarks on result:
other: Flowrate 24 mL/h. Mean of 10 samples. CV= 38%
Water solubility:
0.015 mg/L
Temp.:
20 °C
pH:
7
Remarks on result:
other: Flowrate 12 mL/h. Mean of 10 samples. CV= 6.4%.
Details on results:
The coefficient of variation (CV) (n = 10) at a flow rate of 24 mL/h and 12 mL/h was 38% and 6.1%, respectively. The criterion that coefficient of variation of at least five samples at each flow rate should be ≤ 30% was therefore not met. A second criterion that mean values obtained from two tests with different flows should not differ by more than 30% is considered more important. Since this criterion was met (difference was 3.3%), the results were accepted and the mean was reported as the water solubility of the substance: 15 µg/L.

Any other information on results incl. tables

- No test substance was detected in the samples from the blank column.

- Results for the first disregarded study:

Flowrate 24 mL/h: 0.0129 mg/L

Flowrate 12 mL/h: 0.0212 mg/L

Mean: 0.017 mg/L

(Flow rate 6 mL/h: no test substance detected)

The maximum difference (MD) on the mean values: 49%

Applicant's summary and conclusion

Conclusions:
Interpretation of results (migrated information): insoluble (< 0.1 mg/L)
The water solubility of the substance at 20°C has been determined as 15 µg/L using the column elution method (GLP-compliant study in accordance with EC A.6, OECD 105 and OPPTS 830.7840). The pH was 6.9-7.0.