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Diss Factsheets

Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Original reference in foreign language

Data source

Reference
Reference Type:
publication
Title:
Toxicity of titanium tetrachloride
Author:
Yang H; Zhang J, Feng S, Wang X, Chen Y, Liu Y
Year:
1997
Bibliographic source:
Weisheng Dulixue Zazhi 11(2): 131-133

Materials and methods

Principles of method if other than guideline:
Rats were exposed to the test substance, an oral LD50 value was determined
GLP compliance:
not specified
Test type:
standard acute method

Test material

Constituent 1
Chemical structure
Reference substance name:
Titanium tetrachloride
EC Number:
231-441-9
EC Name:
Titanium tetrachloride
Cas Number:
7550-45-0
Molecular formula:
Cl4Ti
IUPAC Name:
titanium tetrachloride
Details on test material:
unknown

Test animals

Species:
rat
Strain:
other: unknown
Sex:
male/female
Details on test animals or test system and environmental conditions:
TEST ANIMALS
- Weight at study initiation: 180-220 g

ENVIRONMENTAL CONDITIONS
unknown

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
other: unknown
Details on oral exposure:
unknown
Doses:
unknown
No. of animals per sex per dose:
unknown
Control animals:
other: unknown
Details on study design:
unknown
Statistics:
unknown

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
586.76 mg/kg bw
95% CL:
>= 510.15 - <= 678.87
Mortality:
unknown
Clinical signs:
other: unknown
Gross pathology:
unknown

Applicant's summary and conclusion