Registration Dossier
Registration Dossier
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EC number: 405-490-3 | CAS number: 613-62-7 BENZYL-2-NAPHTHYLETHER; BETA-NAPHTHYLBENZYLETHER (BON); BNE; BON; NIPAFAX BNE; SENSLON-50; ZO-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: reference from NICNAS file
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Unnamed
- Year:
- 1 990
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: unspecified OECD guideline
- GLP compliance:
- not specified
- Test type:
- standard acute method
- Limit test:
- yes
Test material
- Reference substance name:
- 2-(phenylmethoxy)naphthalene
- EC Number:
- 405-490-3
- EC Name:
- 2-(phenylmethoxy)naphthalene
- Cas Number:
- 613-62-7
- Molecular formula:
- C17 H14 O
- IUPAC Name:
- 2-(benzyloxy)naphthalene
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: SD
- Sex:
- male/female
Administration / exposure
- Vehicle:
- maize oil
- Remarks:
- 20% (w/v)
- Doses:
- 2000 mg/kg bw
- No. of animals per sex per dose:
- 5
- Details on study design:
- The observation period was 14 days.
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- >= 2 000 mg/kg bw
- Based on:
- test mat.
- Remarks on result:
- other: No deaths, clinical signs of toxicity or treatment-related macroscopic lesions were observed.
Applicant's summary and conclusion
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