2-(2-(2-butoxyethoxy)ethoxy)ethanol

Epidemiological data

Administrative data

Endpoint:

epidemiological data

Type of information:

experimental study

Adequacy of study:

supporting study

Reliability:

2 (reliable with restrictions)

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

1983

Materials and methods

Study type:

case control study (prospective)

Endpoint addressed:

repeated dose toxicity: inhalation

repeated dose toxicity: dermal

Test guideline

Qualifier:

no guideline required

Principles of method if other than guideline:

NIOSH (NOES Survey 1981-1983) has statistically estimated that 25,310 workers (50 of these are female) are potentially exposed to triethylene glycol monobutyl ether or (2-(2-(2-butoxyethoxy)ethoxy)ethanol) in the US.

GLP compliance:

not specified

Test material

Test material information

Constituent 1

Reference substance name:

2-(2-(2-butoxyethoxy)ethoxy)ethanol

EC Number:

205-592-6

EC Name:

2-(2-(2-butoxyethoxy)ethoxy)ethanol

Cas Number:

143-22-6

Molecular formula:

C10H22O4

IUPAC Name:

2-[2-(2-butoxyethoxy)ethoxy]ethanol

Constituent 2

Reference substance name:

triethylene glycol monobutyl ether

IUPAC Name:

triethylene glycol monobutyl ether

Method

Type of population:

occupational

Ethical approval:

confirmed, but no further information available

Exposure assessment:

estimated

Results and discussion

Results:

Probable Routes of Human Exposure:
NIOSH (NOES Survey 1981-1983) has statistically estimated that 25,310 workers (50 of these are female) are potentially exposed to triethylene glycol monobutyl ether or (2-(2-(2-butoxyethoxy)ethoxy)ethanol) in the. Occupational exposure to triethylene glycol monobutyl ether may occur through inhalation and dermal contact with this compound at workplaces where triethylene glycol monobutyl ether is produced or used (SRC). Monitoring and use data indicate that the general population may be exposed to triethylene glycol monobutyl ether via ingestion of contaminated drinking water, and dermal contact with products containing triethylene glycol monobutyl ether.

Any other information on results incl. tables

National Occupational Exposure Survey
(1981 - 1983)

Estimated Numbers of Employees Potentially Exposed to Specific Agents by 2-Digit Standard Industrial Classification (SIC)*

 

nt Name		ETHANOL, 2-(2-(2-BUTOXYETHOXY)ETHOXY)-
CAS #		143-22-6
RTECS #		KJ9450000
Agent Code		M0984

 

Industry Description (1972)	Total # Employees (Male & Female)	Total # Female Employees
OIL AND GAS EXTRACTION	4,843
GENERAL BUILDING CONTRACTORS	828
SPECIAL TRADE CONTRACTORS	622
FOOD AND KINDRED PRODUCTS	188
TEXTILE MILL PRODUCTS	75
FABRICATED METAL PRODUCTS	500	13
MACHINERY, EXCEPT ELECTRICAL	1,342	31
ELECTRIC AND ELECTRONIC EQUIPMENT	9
TRANSPORTATION EQUIPMENT	1,395	6
TRANSPORTATION BY AIR	422
ELECTRIC, GAS, AND SANITARY SERVICES	236
WHOLESALE TRADE - DURABLE GOODS	1,653
AUTOMOTIVE DEALERS & SERVICE STATIONS	9,614
PERSONAL SERVICES	392
AUTO REPAIR, SERVICES, AND GARAGES	2,833
HEALTH SERVICES	357
25,310	5

 

*(1)By survey design, not all 2-digit SICs were surveyed.(2)The estimates for each 2-digit SIC apply only to the3- and 4-digit SICs surveyedwithin the 2-digit SIC. Not all SICs were surveyed.(3)When using the estimates,standard errors associated with estimatesshould be considered.(4)Potential exposures to a chemical agent are categorized as actual (i.e., the surveyor observed the use of the specific agent) or tradename (i.e., the surveyor observed the use of a tradename product known to contain the specific agent). The estimates presented in the table combine both categories.

Applicant's summary and conclusion

Conclusions:

NIOSH (NOES Survey 1981-1983) has statistically estimated that 25,310 workers (50 of these are female) are potentially exposed to triethylene glycol monobutyl ether or (2-(2-(2-butoxyethoxy)ethoxy)ethanol) in the US. Occupational exposure to triethylene glycol monobutyl ether may occur through inhalation and dermal contact with this compound at workplaces where triethylene glycol monobutyl ether is produced or used (SRC). Monitoring and use data indicate that the general population may be exposed to triethylene glycol monobutyl ether via ingestion of contaminated drinking water, and dermal contact with products containing triethylene glycol monobutyl ether.