Registration Dossier
Registration Dossier
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 936-795-4 | CAS number: -
Skin irritation / corrosion
Administrative data
- Endpoint:
- skin irritation: in vivo
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 2008
- Reliability:
- 1 (reliable without restriction)
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 2 008
- Report date:
- 2008
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
- GLP compliance:
- yes (incl. QA statement)
- Remarks:
- See certificate in study report
Test material
- Reference substance name:
- 864970-33-2
- Cas Number:
- 864970-33-2
- IUPAC Name:
- 864970-33-2
Constituent 1
Test animals
- Species:
- rabbit
- Strain:
- New Zealand White
Test system
- Type of coverage:
- semiocclusive
- Preparation of test site:
- other: Clipped
- Vehicle:
- water
- Controls:
- not required
- Amount / concentration applied:
- 0.5 grams
- Duration of treatment / exposure:
- 4 hours
- Observation period:
- 1 hour, 24 hours and 48 hours
- Number of animals:
- 3
Results and discussion
In vivo
Results
- Irritation parameter:
- primary dermal irritation index (PDII)
- Basis:
- mean
- Time point:
- other: 1, 24, 48, 72 h
- Score:
- 0.2
- Reversibility:
- fully reversible within: 48 h
- Irritant / corrosive response data:
- Very slight erythema was noted at two treated skin one hour after patch removal and at one treated skin at the 24-hour observation. One treated skin appeared normal throughout the study, one other treated skin appeared normal at the 24-hour observation and the remaining treated skin appeared normal at the 48_hour observation. No corrosive effects were noted.
Applicant's summary and conclusion
- Interpretation of results:
- study cannot be used for classification
- Remarks:
- Migrated information
- Conclusions:
- The organic part of PACTT, 2 Na is not classified as irritant for skin. As the mineral part of PACTT, 2 Na, Sodium Bromide, is not either classified as irritant for skin, it can be concluded that the multi-constituent substance has not to be classified as irritant for skin.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
