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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
skin irritation: in vivo
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2008
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2008
Report date:
2008

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 404 (Acute Dermal Irritation / Corrosion)
GLP compliance:
yes (incl. QA statement)
Remarks:
See certificate in study report

Test material

Constituent 1
Reference substance name:
864970-33-2
Cas Number:
864970-33-2
IUPAC Name:
864970-33-2

Test animals

Species:
rabbit
Strain:
New Zealand White

Test system

Type of coverage:
semiocclusive
Preparation of test site:
other: Clipped
Vehicle:
water
Controls:
not required
Amount / concentration applied:
0.5 grams
Duration of treatment / exposure:
4 hours
Observation period:
1 hour, 24 hours and 48 hours
Number of animals:
3

Results and discussion

In vivo

Results
Irritation parameter:
primary dermal irritation index (PDII)
Basis:
mean
Time point:
other: 1, 24, 48, 72 h
Score:
0.2
Reversibility:
fully reversible within: 48 h
Irritant / corrosive response data:
Very slight erythema was noted at two treated skin one hour after patch removal and at one treated skin at the 24-hour observation. One treated skin appeared normal throughout the study, one other treated skin appeared normal at the 24-hour observation and the remaining treated skin appeared normal at the 48_hour observation. No corrosive effects were noted.

Applicant's summary and conclusion

Interpretation of results:
study cannot be used for classification
Remarks:
Migrated information
Conclusions:
The organic part of PACTT, 2 Na is not classified as irritant for skin. As the mineral part of PACTT, 2 Na, Sodium Bromide, is not either classified as irritant for skin, it can be concluded that the multi-constituent substance has not to be classified as irritant for skin.