Propanoic acid, 2,2,3-trifluoro-3-[1,1,2,2,3,3-hexafluoro-3-(trifluoromethoxy)propoxy]-, methyl ester

Vapour pressure

Administrative data

Endpoint:

vapour pressure

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2008

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: Study was carefully performed using standard instrumentation according to an ASTM method. However, the OECD method specifies somewhat different procedures than the ASTM method, and it was not conducted in accord with GLP guidelines.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Report date:

2008

Materials and methods

Test guideline

Qualifier:

according to guideline

Guideline:

other: ASTM E1719-97 (Vapor Pressure Measurement by Ebulliometry) and ASTM D1120-94 (Standard Test Method for Boiling Point of Engine Coolants)

Deviations:

not specified

GLP compliance:

no

Type of method:

dynamic method

Test material

Test material information

Constituent 1

Reference substance name:

MeDONA

IUPAC Name:

MeDONA

Details on test material:

- Name of test material (as cited in study report): CF3OC3F6OCFHCF2COOCH3 PF13 Methyl Ester
- Lot/batch no.: 146830-84

Results and discussion

Vapour pressure

Temp.:

20 °C

Vapour pressure:

0.2 kPa

Any other information on results incl. tables

The temperatures measured were that of the pot temperature, rather than distillate, as per ASTM E1719-97 (Vapor Pressure Measurement by Ebulliometry). Figure 1. (Vapor Pressure 1) --> SEE ATTACHMENT 1

The data are fit by the Antoine equation:

ln(Pvap) = A / (T + C) + B

Figure 2. (Vapor Pressure 2) (ln(Pvap) vs 1/(T+C)) --> SEE ATTACHMENT 2

Pvap (mm Hg) = exp(-2686.380034/(T °C + 160) + 15.311790) R²=0.998973 The value of the factor C was determined to be 160 by an iterative correction process. The vapor pressure obtained from this equation is 0.20 Pa (1.47 mm Hg) at 20 °C (68 °F).

Applicant's summary and conclusion

Conclusions:

The extrapolated vapor pressure of MeDONA was determined to be 0.20 kPa at 20 °C

Executive summary:

The vapor pressure of MeDONA was extrapolated from the measured vapor pressures and temperatures for the compound. Measurements were made according to method ASTM E1719-97. Vapor pressure and temperature were measured at a variety of equilibrium points covering a temperature range of ca. 40 °C to ca. 150 °C and fit to the Antoine equation ln(VP) = A/(T+C)+B, where T is the pot temperature in °C. The linear regression equation was VP = exp(-2686.380034/(T °C + 160) + 15.311790). The extrapolated vapor pressure of MeDONA at 20 °C (68 °F) was determined to be 0.20 kPa (1.47 mm Hg).

The study was conducted under method ASTM E1719-97 (Vapor Pressure of Liquids by Ebulliometry). The dynamic method is approved for this endpoint per OECD TG 104§8, however the OECD method specifies somewhat different procedures than the ASTM method. The study was not conducted in accord with GLP guidelines. Therefore, the study is classified as acceptable with restrictions.