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Toxicological information

Acute Toxicity: oral

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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)

Data source

Reference
Reference Type:
other: ECHA inquiry result
Title:
Unnamed
Year:
1999

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 401 (Acute Oral Toxicity)
GLP compliance:
yes
Test type:
standard acute method
Limit test:
yes

Test material

Constituent 1
Chemical structure
Reference substance name:
3-(hydroxyphenylphosphinyl)propanoic acid
EC Number:
411-200-6
EC Name:
3-(hydroxyphenylphosphinyl)propanoic acid
Cas Number:
14657-64-8
Molecular formula:
C9H11O4P
IUPAC Name:
3-[hydroxy(phenyl)phosphoryl]propanoic acid

Test animals

Species:
other: Sprague-DawleyCrl:CD BR VAF

Administration / exposure

Vehicle:
other: The test substance is mixed with distilled water to obtain a 50% conc., 10 ml/Kg

Results and discussion

Effect levels
Sex:
male/female
Dose descriptor:
LD50
Effect level:
> 5 000 mg/kg bw
Mortality:
Male: 5000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 5000 mg/kg bw; Number of animals: 5; Number of deaths: 0
Clinical signs:
other: Signs of toxicity related to dose levels: No substance-related signs of toxicity
Gross pathology:
Effects on organs:
No effects in organs related to the test substance

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU