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Administrative data

Endpoint:
acute toxicity: oral
Type of information:
experimental study
Adequacy of study:
key study
Study period:
25/10/2010 - 19/11/2010
Reliability:
1 (reliable without restriction)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010

Materials and methods

Test guideline
Qualifier:
according to guideline
Guideline:
OECD Guideline 423 (Acute Oral toxicity - Acute Toxic Class Method)
GLP compliance:
no
Test type:
acute toxic class method

Test material

Constituent 1
Chemical structure
Reference substance name:
2-aminododecan-1-ol hydrochloride (1:1)
EC Number:
687-797-4
Cas Number:
23551-91-9
Molecular formula:
C12H27NO.HCl
IUPAC Name:
2-aminododecan-1-ol hydrochloride (1:1)

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
female

Administration / exposure

Route of administration:
oral: gavage
Vehicle:
water
Doses:
2000 mg/kg + 300 mg/kg
No. of animals per sex per dose:
3 rats => 2000 mg/kg
+ 3 rats => 300 mg/kg
+ 3 rats => 300 mg/kg
Control animals:
no

Results and discussion

Effect levels
Sex:
female
Dose descriptor:
LD50
Effect level:
> 300 - <= 2 000 mg/kg bw

Applicant's summary and conclusion

Interpretation of results:
harmful
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
Acute oral toxicity = CLP category 4 : harmful if swallowed.

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