Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
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EC number: 700-578-0 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- adverse effect observed (sensitising)
- Additional information:
The Buehler test is a non-adjuvant method involving the induction phase topical application only. It gives qualitative assessment of skin sensitization after induction - rest - revelation phases. The test was performed using olive oil as vehicule.
The LLNA is a method involving the lymphocyte proliferative responses indused in regional lymph nodes. It gives a quantitative assessment of skin sensitization after an induction phase. The test was performed using dimethylformamide (DMF) as vehicule.
Migrated from Short description of key information:
Sepisol Fast Violet 2B was not found tobe sensitizing with the Buehler test but was considered to be sensitizing with the LLNA test.
Justification for classification or non-classification
The LLNA is the reference test method. Futhermore, there is no hindsight with this organiocopper dye molecules so it was not possible to choose which test fits the best.
As a result the Sepisol Fast Violet 2B is considered to be sensitizing cat. 1A.
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