Registration Dossier

Diss Factsheets

Environmental fate & pathways

Adsorption / desorption

Currently viewing:

Administrative data

Endpoint:
adsorption / desorption
Remarks:
other: (Q)SAR
Type of information:
(Q)SAR
Adequacy of study:
supporting study
Study period:
An assessment of the adsorption coefficient of the test item was carried out on 08 February 2010.
Reliability:
3 (not reliable)
Rationale for reliability incl. deficiencies:
other: As neither of the computer-based prediction methods contains titanium salts in their data sets, the reliability of the results is uncertain.
Justification for type of information:
QSAR prediction: migrated from IUCLID 5.6
Cross-reference
Reason / purpose for cross-reference:
reference to other study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2010

Materials and methods

Test guideline
Qualifier:
no guideline followed
Guideline:
other: computer-based prediction software, KOCWIN, version 2.00 (February 2009), © 2000-2008 U.S. Environmental Protection Agency.
Deviations:
no
Principles of method if other than guideline:
The adsorption coefficient was estimated using computer-based prediction software, KOCWIN, version 2.00 (February 2009), © 2000-2008 U.S. Environmental Protection Agency.
GLP compliance:
no
Type of method:
other: computer-based prediction software, KOCWIN, version 2.00 (February 2009), © 2000-2008 U.S. Environmental Protection Agency.
Media:
other: Not applicable

Test material

Constituent 1
Reference substance name:
E0286P/040A
IUPAC Name:
E0286P/040A
Constituent 2
Reference substance name:
Ti(C10H19O2)x(C3H3O)y; where 0 ≤ x ≤ 4, 0 ≤ y ≤ 4, x + y = 4
IUPAC Name:
Ti(C10H19O2)x(C3H3O)y; where 0 ≤ x ≤ 4, 0 ≤ y ≤ 4, x + y = 4
Details on test material:
Sponsor's identification: E0286P/040A
Description : amber coloured viscous liquid
Batch number : E0286P/040A/01
Date received : 20 July 2009
Storage conditions: room temperature in the dark

Study design

Test temperature:
Not applicable

HPLC method

Details on study design: HPLC method:
Not applicable

Batch equilibrium or other method

Analytical monitoring:
no
Details on sampling:
Not applicable
Details on matrix:
Not applicable
Details on test conditions:
Not applicable
Computational methods:
Not applicable

Results and discussion

Adsorption coefficient
Type:
log Koc
Value:
4.6 - 9.5
Remarks on result:
other: Using computer-based prediction software, the log adsorption coefficient of the test item was estimated to be in the range 4.6 to 9.5 (MCI Method) and in the range 0.9 to 8.1 (Log Kow method).

Results: HPLC method

Details on results (HPLC method):
Using computer-based prediction software, the log adsorption coefficient of the test item was estimated to be in the range 4.6 to 9.5 (MCI Method) and in the range 0.9 to 8.1 (Log Kow method).

Results: Batch equilibrium or other method

Transformation products:
not measured

Applicant's summary and conclusion

Validity criteria fulfilled:
no
Remarks:
As neither of the computer-based prediction methods contains titanium salts in their data sets, the reliability of the results is uncertain.
Conclusions:
Using computer-based prediction software, the log adsorption coefficient of the test item was estimated to be in the range 4.6 to 9.5 (MCI Method) and in the range 0.9 to 8.1 (Log Kow method).
Overall, it is anticipated that adsorption in the environment would be low, generally due to the low solubility of the test item in water (see Harlan Laboratories Ltd, Shardlow, Project Number 2184/0005). However, once the test item does become dissolved/ dispersed in water (e.g. by a water-miscible co-solvent), it is anticipated that the test item would then decompose rapidly, forming titanium dioxide, isopropanol and neodecanoic acid/neodecanoate. Assessment of the adsorption coefficient of any potential decomposition products is outside the scope of this report
Executive summary:

Using computer-based prediction software, the log adsorption coefficient of the test item was estimated to be in the range 4.6 to 9.5 (MCI Method) and in the range 0.9 to 8.1 (Log Kow method).

Overall, it is anticipated that adsorption in the environment would be low, generally due to the low solubility of the test item in water (see Harlan Laboratories Ltd, Shardlow, Project Number 2184/0005). However, once the test item does become dissolved/ dispersed in water (e.g. by a water-miscible co-solvent), it is anticipated that the test item would then decompose rapidly, forming titanium dioxide, isopropanol and neodecanoic acid/neodecanoate. Assessment of the adsorption coefficient of any potential decomposition products is outside the scope of this report.

As neither of the computer-based prediction methods contains titanium salts in their data sets, the reliability of the results is uncertain.

Categories Display