Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 701-379-1 | CAS number: -
Endpoint summary
Administrative data
Description of key information
Additional information
Short-term toxicity to fish
Reaction Product of Bisphenol A diglycidylether (BADGE) with a mixture of IPDA and MXDA was not tested for short-term ecotoxicological properties. Instead, a read-across approach was applied for short-term toxicity to fish using data of symmetrical epoxy amine adducts Reaction products of IPDA with bisphenol A diglycidylether (BADGE) and Reaction products of MXDA with bisphenol A diglycidylether (BADGE), as these substances were considered to show similar ecotoxicological properties. Both symmetrical epoxy amine adducts were tested for short-term toxicity to fish according to EU method C.1. Determined worst-case toxicity values for the asymmetrical epoxy amine adduct were a 96-h LC50 of 1.62 mg/L and a 96-h NOEC of 0.96 mg/L.
Short-term toxicity to aquatic invertebrates
Reaction Product of Bisphenol A diglycidylether (BADGE) with a mixture of IPDA and MXDA was not tested for short-term ecotoxicological properties. Instead, a read-across approach was applied for short-term toxicity to aquatic invertebrates using data of symmetrical epoxy amine adducts Reaction products of IPDA with bisphenol A diglycidylether (BADGE) and Reaction products of MXDA with bisphenol A diglycidylether (BADGE), as these substances were considered to show similar ecotoxicological properties. Both symmetrical epoxy amine adducts were tested for short-term toxicity to invertebrates according to EU method C.2. Determined worst-case toxicity values for the asymmetrical epoxy amine adduct Reaction Product of Bisphenol A diglycidylether (BADGE) with IPDA and MXDA were a 48-h EC50 of 1.75 mg/L and 48-h NOEC of 0.705 mg/L.
Toxicity to aquatic algae and cyanobacteria
A read-across approach was applied for short-term toxicity to algae using data of symmetrical epoxy amine adducts Reaction products of IPDA with bisphenol A diglycidylether (BADGE) and Reaction products of MXDA with bisphenol A diglycidylether (BADGE), as these substances were considered to show similar ecotoxicological properties as compared to the unsymmetrical adduct BADGE with IPDA and MXDA. The ErC50 (based on growth rate) was determined to be 2.11 mg/L in the read-across study with Reaction products of MXDA with bisphenol A diglycidylether (BADGE) (CAS 113930-69-1) and 3.13 mg/L in the read-across study with IPDA (CAS 38294-64-3). The ErC10 was determined to be 1.55 mg/L (MXDA) and 1.99 mg/L (IPDA), respectively.
Toxicity to microorganisms
Reaction Product of Bisphenol A diglycidylether (BADGE) with IPDA and MXDA was not tested for short-term ecotoxicological properties. Instead, a read-across approach was applied for short-term toxicity to microorganisms test with the symmetrical epoxy amine adducts Reaction products of IPDA with bisphenol A diglycidylether (BADGE) and Reaction products of MXDA with bisphenol A diglycidylether (BADGE), as these substances were considered to show similar ecotoxicological properties. Both substances were tested for toxicity to microorganisms according to EU method C. 11. Applying toxicity values from the most toxic symmetrical adduct, the EC50 (3 h) value for the asymmetrical adduct Reaction Product of Bisphenol A diglycidylether (BADGE) with IPDA and MXDA was 72.63 mg/L and the NOEC was 31 mg/L.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
