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Administrative data

Endpoint:
boiling point
Type of information:
experimental study
Adequacy of study:
key study
Study period:
Between 07 February and 15 March 2012
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: see 'Remark'
Remarks:
Study conducted in compliance with agreed protocols, with no or minor deviations from standard test guidelines and/or minor methodological deficiencies, which do not affect the quality of the relevant results. The study report was conclusive, done to a valid guideline and the study was conducted under GLP conditions.

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
2012

Materials and methods

Test guidelineopen allclose all
Qualifier:
according to guideline
Guideline:
EU Method A.2 (Boiling Temperature)
Version / remarks:
using a procedure designed to be compatible with Method A2 Boiling Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 103 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
Deviations:
no
Qualifier:
according to guideline
Guideline:
OECD Guideline 103 (Boiling point/boiling range)
Version / remarks:
using a procedure designed to be compatible with Method A2 Boiling Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 103 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.
Deviations:
no
GLP compliance:
yes
Type of method:
differential scanning calorimetry

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Identification: BMS-528235-01
Description: Off white powder
Batch: 1L63487N
Purity: 98.6 %
Expiry Date: 27 November 2014
Storage Conditions: Room temperature in the dark

Results and discussion

Boiling point
Decomposition:
yes
Decomp. temp.:
>= 200 °C
Remarks on result:
other: The test item has been determined to decompose from approximately 200 °C (473 K) at approximately 103.7 kPa. As the test item decomposed, no value for boiling temperature could be determined.

Any other information on results incl. tables

Please see Attachment 1 for the Thermograms and Thermographic data for determinations 1 and 2.

Applicant's summary and conclusion

Conclusions:
The test item has been determined to decompose from approximately 200 °C (473 K) at approximately 103.7 kPa. As the test item decomposed, no value for boiling temperature could be determined.
Executive summary:

The determination was carried out by differential scanning calorimetry (DSC), using a procedure designed to be compatible with Method A2 Boiling Temperature of Commission Regulation (EC) No 440/2008 of 30 May 2008 and Method 103 of the OECD Guidelines for Testing of Chemicals, 27 July 1995.

The temperature accuracy of the DSC was assessed using an indium reference standard (purity*: 100 %) *value quoted by supplier. The melting temperature was determined to be 156.73 ºC and within the defined tolerance (156.6 ± 0.5 ºC). The DSC was therefore considered acceptable for use.

Conclusion

The test item has been determined to decompose from approximately 200 °C (473 K) at approximately 103.7 kPa. As the test item decomposed, no value for boiling temperature could be determined.