Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 205-736-8 | CAS number: 149-30-4
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics in vivo
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: A scientific study.
Data source
Reference
- Reference Type:
- publication
- Title:
- Unnamed
- Year:
- 1 989
Materials and methods
- Principles of method if other than guideline:
- Intravenous injection, determination of metabolites .
- GLP compliance:
- no
Test material
- Radiolabelling:
- yes
Test animals
- Species:
- rat
- Sex:
- male/female
Administration / exposure
- Route of administration:
- intravenous
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- No unchanged mercaptobenzothiazole was detected in urine, and two metabolites were identified: thioglucuronide and sulfonic acid derivatives (72 hours after intravenous administration, 90.9 -100% appeared in urine of rats).
- Executive summary:
No unchanged mercaptobenzothiazole was detected in urine, and two metabolites were identified: thioglucuronide and sulfonic acid derivatives (72 hours after intravenous administration, 90.9 -100% appeared in urine of rats).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
