Registration Dossier
Registration Dossier
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EC number: 810-156-9 | CAS number: 1236049-43-6
Endpoint summary
Administrative data
Description of key information
Additional information
The data submitter has no data, even after literature search on the substance (R)-3 -amino-1 -butanol (S)-mandelic acid salt (CAS 1236049 -43 -6) to properly derive classification and labeling. Nevertheless, in order to address aquatic toxicity endpoints of the test item, reference to the racemic mixture of 3 -Amino-butan-1-ol (CAS 2867 -59 -6) was made for read-across purposes to the salt consitituents (3R)-3-Amino-1-butanol, (CAS 61477 -40 -5) and reference to (R) mandelic acid (CAS 611 -71 -2) was made for read-across purposes to the salt constituents (S) mandelic acid (CAS 17199 -29 -0).
For 3 -Amino-butan-1 -ol (CAS 2867 -59 -6) the following data on aquatic toxicity are available. A Limit-test on short term toxicity to aquatic invertebrates reveals EC50>100 mg/L (BASF SE 2014, 50E0406/13X125). A screening test on toxicity to aquatic algae and cyanobacteria reveals an EC50>10 - < 100mg/L (BASF SE 2014, 86E0406/13G195). An a study on toxicity to microorganisms, which reveals an EC20 of 780mg/L (BASF SE 2014, 08G0406/13G073). For (R) mandelic acid (CAS 611 -71 -2) the following data are available. A test on short-term toxicity to aquatic invertebrates reveals EC50> 100 mg/L (BASF AG 2002, 02/0061/50/1). And a study on toxicity to microorganisms reveal EC20>1000mg/L (BASF AG 2002, 02/0061/08/1). Due to these available results the substance (R)-3 -amino-1 -butanol (S)-mandelic acid salt (CAS 1236049 -43 -6) is considered as acutely harmful to aquatic organims.Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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